hrp0094p2-4 | Adrenals and HPA Axis | ESPE2021

Serum Sex Hormone Binding Globulin Levels, But Not 4-Hour Profile of 17-Oh Progesterone, Would Be Useful in Monitoring Children with Congenital Adrenal Hyperplasia

Besci Ozge , Erbas Ibrahim Mert , Kume Tuncay , Acinikli Kubra Yuksek , Abacı Ayhan , Bober Ece , Demir Korcan ,

Background: There exists no gold standard for adjustment of treatment in congenital adrenal hyperplasia. Clinicians try to avoid over-and undertreatment by considering various indicators. We aimed to investigate the sampling times of 17-hydroxyprogesterone (17-OHP) and the use of sex hormone-binding globulin (SHBG) as a monitoring parameter, the association of which was not studied with clinical features. Materials and Methods: This cross-sectional study inclu...

hrp0094p2-353 | Pituitary, neuroendocrinology and puberty | ESPE2021

Clinical course of primary empty sella in children: a 10-year single-center experience

Besci Ozge , Yasar Elif , Mert Erbas Ibrahim , Yuksek Acinikli Kubra , Demir Korcan , Bober Ece , Abacı Ayhan ,

Background: Various studies, mostly conducted in adults, evaluated the hormonal axis in primary empty sella (PES), and reported different forms of pituitary deficiencies. We report our 10-year experience of pediatric cases with PES, investigating the pituitary function, associated impairments, and responses to treatments.Materials and Methods: We reviewed 10,560 cranial and 325 pituitary magnetic resonance imagings (MRIs) performed in ou...

hrp0094p1-64 | Diabetes B | ESPE2021

Initial Neutrophil/Lymphocyte and Lymphocyte/Monocyte Ratios Can Predict Future Insulin Need in Newly Diagnosed Type 1 Diabetes Mellitus

Erbaş Ibrahim Mert , Hajikhanova Aygun , Besci Ozge , Acinikli Kubra Yuksek , Demir Korcan , Bober Ece , Abacı Ayhan ,

Background: The exact mechanism of the partial clinical remission in type 1 diabetes mellitus (T1DM) has not been elucidated yet. The severity of the inflammation at the time of diagnosis may have an impact on the occurrence or duration of this phase.Objective: We aimed to investigate the relationship between hematological inflammatory parameters at the time of diagnosis in children and adolescents with T1DM and the need...

hrp0097rfc6.2 | Pituitary, neuroendocrinology and puberty 1 | ESPE2023

Psychosocial Evaluation of Girls with Rapidly Progressive Puberty Presenting with Early Menarche

Yüksek Acinikli Kübra , Besci Ozge , Akın Kağızmanlı Gözde , Gündoğan Nazan , Unutmaz Güldal , Berkay Esen Ahmet , Alşen Güney Sevay , Korcan Demir Korcan , Böber Ece , Abacı Ayhan

Key words: early puberty, mood change, GnRH analogueIntroduction-Aim: In cases with early puberty, neuroendocrine, physical, and psychological changes are considered to result in several mood disorders. The aim of this research was to assess the mental problems of pubertal girls with rapidly progressive puberty (RPP) with menarche before the 10 years of age. To the best of our knowledge, there is no similar prospective c...